Hemorrhoids are dilated engorged submucosal veins in the anal canal. There are several therapeutic modalities for haemorrhoids but surgical treatment is considered to be most effective. Harmonic scalpel hemorrhoidectomy was compared with conventional in terms of benefits and complication. Methods: The aim of our study was to compare harmonic scalpel haemorrhoidectomy with conventional in terms of intraoperative and postoperative factors for the treatment of grade III and IV piles. Results: In our study of 15 patients average time was 29.4±2.84 minutes while it was 15.32±2.83 minutes in the case group. The mean blood loss was 33.72 ± 1.28 ml, 7.89 ± 1.15 ml in the control and case group respectively. Postoperative pain with VAS Score was 8.38±0.74 in the control group and in case group on the first postoperative day(POD1) was 5.29 ± 0.72. The dose of analgesia was less in the case group. The postoperative wound site soakage was less in the case study, early ambulation and return to normal work was faster in case study group. Conclusion: Harmonic scalpel is a simple, painless, bloodless safe and effective method in terms of blood loss, postoperative pain and early return to normal work because of less lateral thermal injury. Keyword: Haemorrhoidectomy, Harmonic scalpel, Early ambulation, case group, control group.