Presently breast cancer detection is a very important role for world young women to save and extended to the life. The new proposed technology is anisotropic median diffusion filter for denoising low-signal-to-noise molecular images. This filter, which incorporates a median filter into the diffusion steps, is called an anisotropic median-diffusion filter. This hybrid filter achieved much better noise suppression and reduced gausssian noise, spikes compared with the anisotropic diffusion filter when it was tested on an image created based on a molecular image model. We prepare a algorithm detect of Brest Cancer early with molecular imaging ADME uses to the (i.e) uses of density of molecular in this study we develop a mathematical mode for ADME and together the breast cancer molecular image and analysis that performance .The anisotropic median-diffusion filter also achieved good smoothen in inner area and outer area boundry of the molecular images. In this filter particularly useful for non linear molecular images.