Nanotechnology is the study of extremely small structures. The prefix “nano” is a Greek word which means “dwarf”.  The word “nano” means very small or miniature size. Nanotechnology encompasses the production and application of physical, chemical, and biological systems at scales ranging from individual atoms or molecules to submicron dimensions. Nanotechnology applications that could impact the global market in agricultural, pharmaceutical, and other non-fuel commodities are being developed Currently, nanotechnology is described as a revolutionary discipline in terms of its possible impact on industrial applications. Even today various disease like cancer, cardiovascular diseases, diabetes, Parkinson’s disease, multiple sclerosis and Alzheimer’s disease, as well as complex illnesses pose a major problem for mankind.Nanotechnology can deliver medicine or drugs into specific parts of the human body, thereby making them more effective and less harmful to other parts of the body.Once the nanoshells enter into tumor cells and radiation treatment is applied, they absorb the energy and heat up enough to kill the cancer cells. To synthesize silver nanoparticles using medicinal plants in and around Vellore district, Tamilnadu. The screening on the leaf extract of the selected medicinal plant to evaluate the optimal synthesis of silver nanoparticles revealed that leaves extract of the plant Aristolochia bracteata was found to be an effective reducing agent of Ag ions to produce silver nanoparticles of nanosized.The aqueous leaf extracts were employed as reducing agents for the development of silver nanoparticles from silver nitrate solutionThe aim of the present study was to evaluate the antibacterial activity of synthesized silver nanoparticles from Aristalochia bracteata leaf extract. Three Bacterial pathogens Bacillus subtilis, Staphylococcus aureus, Salmonella typhi were used for the experimental study was found that the minimum inhibitory concentration (MIC) of silver nanoparticles from Aristalochia bracteata aqueous extract was 25µg in the six bacterial strains.